Speaker：Qing Yu （俞青），中科院神經所研究員

Time： 13:30-15:30, Dec. 15th, 2023

Venue：Room 1113, Wang Ke Zhen Bldg

Host: Lushan Zhu

Abstract

Working memory, the ability to temporarily maintain and manipulate information to serve flexible behavioral goals, is central to human intelligence and remains a fundamental research question in the field of cognitive neuroscience. Recent work has pointed to the involvement of a distributed cortical network, including sensory, parietal, and frontal cortex, in maintaining information during working memory. However, how this distributed network contributes to the internal generation and manipulation of memorized information has remained poorly understood. In this talk, I will present our recent work on characterizing the functional differences between sensory, parietal, and frontal cortex in working memory. Using functional magnetic resonance imaging (fMRI) and electroencephalography (EEG), I will first demonstrate a domain-general contribution of parietal cortex to information generation (i.e., mental imagery) and manipulation in working memory. Next, I will demonstrate how lateral frontal cortex functions fundamentally differently from medial temporal lobe and medial frontal cortex during memory maintenance and manipulation. Lastly, if time permits, I will demonstrate our simulation of the manipulation process using Recurrent Neural Networks (RNNs) and discuss the potential neuronal mechanisms.

Bio

俞青博士于2011年獲得beat365心理學與數學學士雙學位，2016年獲得美國達特茅斯學院認知神經科學博士學位，2016-2020年于美國威斯康星大學麥迪遜分校先後從事博士後與研究科學家的研究工作，2020年9月起擔任中國科學院腦科學與智能技術卓越創新中心（神經科學研究所）研究員。俞青博士的工作結合多模态腦成像技術（功能性核磁共振成像、腦磁圖、頭皮腦電、顱内腦電）、行為測量、數學模型等多學科手段，系統地探究記憶與想象的神經機制。研究成果以第一作者或通訊作者發表于Current Biology (2019)，PLOS Biology (2020a,2020b)，Cell Reports (2023)，The Journal of Neuroscience (2018,2023)，Cerebral Cortex (2019)，NeuroImage (2017)等期刊。擔任Journal of Cognitive Neuroscience的顧問編輯。