Qi Chen, Ph.D Professor, South China Normal University

時間： 2018-01-22 10:00 - 11:30

地點： Room 1113, Wang Kezhen Building

Abstract: Impaired object naming is a core deficit in post-stroke aphasia, which can manifest as errors of commission – producing an incorrect word or a nonword – or as errors of omission – failing to attempt to name the object. Detailed behavioral, computational, and neurological investigations of errors of commission have played a key role in development of neurocognitive models of word production. In contrast, the neurocognitive basis of omission errors is radically underspecified despite being a prevalent phenomenon in aphasia and other populations. The prevalence of omission errors makes their neurocognitive basis important for characterizing an individual’s deficits and, ideally, for personalizing treatment and evaluating treatment outcomes. The present study leveraged established relationships between lesion location and errors of commission to investigate omission errors in picture naming. Omission error rates from the Picture Naming Test for 123 individuals with post-stroke aphasia were analyzed using support vector regression lesion-symptom mapping. Omission errors were most strongly associated with left frontal and mid-anterior temporal lobe lesions. Computational model analysis further showed that omission errors were positively associated with impaired semantically-driven lexical retrieval rather than phonological retrieval. These results suggest that errors of omission in aphasia predominantly arise from lexical-semantic deficits in word retrieval and selection from a competitor set.

Host: Prof. Fang

報告人簡介：陳琦，教授、博士生導師，比利時根特大學心理學博士。2016年入選首批廣東省青年珠江學者，2017年入選“廣東特支計劃”百千萬工程青年拔尖人才項目。長期緻力于建立語言和數學認知的計算模型。近五年主持和參與國家自然科學（社會科學）基金項目4項和2項省部級項目。目前已Psychological Review，Nature Communications和Cognitive Psychology 等學術期刊發表多篇研究論文。成果獲廣東省哲學社會科學優秀成果一等獎。

2018-01-18

2018-01-18